PROJECT

An integrated psycho-social intervention to improve self- efficacy towards treatment uptake and infection prevention among patients and family caregivers – A multi- centric implementation research study.

January 2024 - December 2025

Objectives:

1) To adapt and evaluate the efficacy of a self- efficacy driven intervention in comparison to the standard of care on primary outcomes: i) improved TB treatment self-efficacy and secondary outcomes improved medication adherence, decreased TB stigma & improved infection control self-management practices and illness perception.
2) To evaluate the efficacy of a self- efficacy driven intervention in comparison to the standard of care on secondary outcomes: improved care givers self-efficacy and secondary outcomes decreased TB stigma and improved infection control self-management practices
3) To evaluate the implementation and mechanisms of self-efficacy driven intervention by assessing acceptability level among patients, caregivers and health care providers.

Study Overview:

The intervention is based on self-efficacy constructs in which the patients and caregivers are intervened to “enable them to execute their own courses of actions, behaviors and self-management skills to effectively deal with challenges and needs of TB disease and treatment. The elements of the proposed intervention is derived from the insights of positively deviant TB patients and their caregivers who had coped up with TB in the best possible way and have exhibited maximum self-efficacy.

Study Approach:

A multi centric Hybrid I mixed-method implementation design to evaluate the preliminary efficacy together with the implementation acceptability of delivering a self- efficacy driven intervention by front line health care staff of NTEP, family care providers and patient champions for improving treatment self-efficacy, decreased stigma improve mental health and infection control self-management practices

Expected Public Health Impact:

The proposed self-efficacy-driven intervention has the potential to provide an integrated, theory-driven and evidence-based psycho-social approach to improve self-efficacy among persons with tuberculosis. By addressing treatment acceptance and uptake, self-care, treatment-related behaviors, and underlying psychosocial needs in a holistic manner, the intervention may contribute to improved treatment engagement and outcomes. Evidence generated from this study could support the pragmatic integration and scale-up of self-efficacy-based interventions within the National Tuberculosis Elimination Programme, thereby strengthening patient-centered TB services and contributing to improved treatment outcomes and progress towards TB elimination in India.