HTAIn

Key Areas of Research

To undertake HTA analysis and provide scientific evidence to implement cost-effective and sustainable new health technologies in the country.

Modelling the macroeconomic benefits of TB and other infectious diseases elimination strategies.

List of ongoing projects

Cost comparison of UniAMP sputum swab and Tongue swab UniAMP MTB for Tuberculosis in India

Cost comparison of MERINAT diagnostic platforms for tuberculosis in India

Cost-effectiveness of Nicotine replacement therapy, Bupropion and Varenicline vs Placebo for smoking cessation in people who smoke tobacco

Costing of Health Services in India (CHSI) 2.0: Collection of Hospital-wise and Speciality-wise Claims Data from PM-JAY Empanelled Private Hospitals in Chennai and Thiruvallur Districts, Tamil Nadu CHSI 2.0 (PGIMER)

Cost-effectiveness of plasma exchange (PLEX) treatment for rodenticide poisoning cases (Yellow Phosphorous) with severe liver injury in Tamil Nadu

Advanced data analysis software (TreeAge), modelling platforms, secure data infrastructure and HTA focused research facilities.

Malaisamy Muniyandi, Karikalan Nagarajan, Karthick Chelvanayagam, Kavitha Rajsekar, Kirti Tyagi, Chandrasekaran Padmapriyadarsini. Cost-effectiveness of BPaL/BPaLM as compared to mixed standard of care Bedaquiline containing regimen for MDR/RR-TB. Indian J Med Res 2025; 162: 581-591.

Malaisamy Muniyandi, Karthick Chelvanayagam, Sahil Abdul Salam, Sathishkumar Vadamalai, Kavitha Rajsekar, Rajeswari Ramachandran, Significant reduction of seizure frequency in patients with drug-resistant epilepsy by vagus nerve stimulation: Systematic review and meta-analysis, Epilepsy Research 2025; 210: 107510.

Mahalingam V, Santhanakrishnan RK, Malaisamy M, Chelvanayagam K, Mathiyazhagan K, Bhaskar A, Nagarajan K, Maria Selvam J, Veeraiah S, Rajsekar K, Tyagi K, Chinnaiyan P. Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu. PLoS One. 2025 Jan 29;20(1): e0318013.

Malaisamy Muniyandi, Karikalan Nagarajan, Kavi Mathiyazhagan, Kirti Tyagi, Kavitha Rajsekar, Chandrasekaran Padmapriyadarsini. Evaluating the cost-effectiveness of Cy-Tb for LTBI in India:a comprehensive economic modelling analysis. International Health 2024; 0: 1–11.

Muniyandi M, Karikalan N, Ravi K, Sengodan S, Krishnan R, Tyagi K, Rajsekar K, Raju S, Selvavinayagam TS. An economic evaluation of implementing a decentralized dengue screening intervention under the National Vector Borne Disease Control Programme in Tamil Nadu, South India. Int Health 2022: ihab045.

M. Muniyandi. Cost effectiveness of population based screening for diabetes and HTN in India. Invited as a resource person for national seminar on Consequences of pandemic outbreak on Indian economy organised by the Department of Economics, Vivekananda College, Thiruvedkam West, Madurai on 29th March 2022.

Muniyandi M, Kirti T, Malkeet S, Prakash V, Karikalan N, Senthilkumar S, Sananthya K, Rajendran K, Kavitha R, Vivekanandan S, Selvavinayagam TS. Economic evaluation of implementing a decentralised Hepatitis B virus diagnostic intervention under National Viral Hepatitis Control Programme in Tamil Nadu, South India. Tropical Medicine and International Health 2021.

Conducting Health Technology Assessment (HTA) studies to support policy decisions of the Department of Health Research (DHR), Government of India.

Providing Technical Support to DHR for HTA for developing a policy perspective for HTA for use in public health programs in the country

Undertake HTA in terms of medical effectiveness, cost effectiveness, appropriateness, efficacy, safety, psychological, social, ethical, organizational and economic aspects

To promote introduction and assessment of new and existing health technologies in the system and will provide support for adoption of health technologies

To build capacity in the country towards Health Technology Assessment