Plasma Efavirenz in HIV-infected children treated with generic antiretroviral drugs in India .

Ramachandran, G.; Hemanth Kumar, A.K.; Vasantha, M.; Shah, I. ; Swaminathan, S.

Indian Pediatrics; 2010; 47; 890-891.           

We measured plasma concentration of efavirenz (EFV) in 16 HIV-infected Indian children receiving antiretroviral treatment at Government ART centres. The mean 12-hour concentration was 2.39 µg/mL (range: 0.72- 7.82 µg/mL). The majority of children treated with generic EFV at currently recommended doses had blood levels within the therapeutic range.

Keywords: Antiretroviral treatment, HIV-infected children, Plasma Efavirenz

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