Large sequence polymorphisms classify Mycobacterium tuberculosis with ancestral spoligotyping patterns.

Flores, L.; Van, T.; Narayanan, S.; Deriemer, K.; Kato-Maeda, M.; Gagneux, S.

Journal of Clinical Microbiology; 2007; 45; 3393-3395.

Abstract: Genomic deletion analysis revealed that strains of Mycobacterium tuberculosis exhibiting spoligotyping pattenrs with almost all spacers present belong either to a strain lineage that includes the W-Beijing strain family or to the ancestral strain lineage of M. tuberculosis .


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