Monocyte antimycobacterial activity before and after Mycobacterium bovis BCG Vaccination in Chingleput, India, and London, United Kingdom.
Shuk Han Cheng; Barry Walker, K.; Douglas Lowrie, B.; Mitchison Denis, A.; Rajiswami.S; Manjula Datta; Prabhakar, R.
Infection and Immunity; 1993; 61; 4501-4503.
Monocytes from purified protein derivative S. Mantoux-negative children and young adults inhibited intracellular growth of Mycobacterium microti more in Chinglelput than in London. Mycobacterium bovis BCG vacacination did not enhance bacteriostasis with the Indians but did so with the Londoners. No evidence was found for involvement of cytokines such as macrophage-activating factor and granulocyte macrophage colony-stimulating factor in the differences.
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