In vitro activity of capreomycin and ciprofloxacin against South Indian isolates of M. tuberculosis.
Venkataraman, P.; Paramasivan, C.N.; Prabhakar, R.
Indian Journal of Tuberculosis; 1993; 40; 21-25.
Mycobacterium tuberculosis isolated from 107 South Indian patients, including 53 isolates sensitive to Streptomycin (S), Isoniazid (H) and Rifampicin (R) and 54 resistant to SHR/HR were tested for their in vitro susceptibility to Capreomycin and Ciprofloxacin. Of these, 3 (6%) SHR sensitive strains and 8 (15%) SHR/HR resistant strains were probably resistant to Capreomycin. However, the difference did not attain statistical significance. Considering Ciprofloxacin, the percentage distributions of the MIC with the different categories of strains were similar, there being no difference between sensitive and resistant strains, the geometric means being 3.7 and 3.8 mcg/ml, respectively.
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