Effect of treatment on maximal expiratory flow rates in tropical eosinophilia.
Kuppu Rao, K.V.; Vijayan, V.K.; Venkatesan, P.; Sankaran, K.
Ceylon Medical Journal; 1993; 38; 78-80.
Maximal expiratory flow rates such as peak expiratory flow rate (PEFR), rates at 25%, 50% and 75% of vital capacity (VE max 25%, VE max 50%, VE max 75%) and forced expiratory flow during the middle half of forced vital capacity (FEF 25-75%) were recorded in 23 patients with tropical eosinophilia (TE) before and after treatment. The mean values of all flow rates were significantly lower (P<0.001) in untreated TE patients compared to predicted values. After three weeks' treatment with diethylcarbamazine, although there was a significant rise in the mean values of all expiratory flow rates (P<0.05) except VE max 75% (P>0.2), all flow rates continued to be significantly lower (P<0.01) at one month than predicted values.
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