Effect of hemoglobin on the growth of mycobacteria and production of siderophores.
Raghu, B.; Raghupati Sarma, G.; Venkatesan, P.
Indian Journal of Pathology and Microbiology; 1993; 36; 376-382.
Hemoglobin is known to support the growth of several bacterial species. The growth and the production of siderophores by 4 strains of mycobacteria in the presence of hemoglobin was studied in vitro . The findings were compared with those obtained in the presence of equivalent concentrations of iron in the medium. Increase in the growth of all 4 strains. This was, however, accompanied by a significant decrease in the production of both exochelins and mycobactins. It was also observed that hemoglobin supported the growth of all strains as well as that with free iron and the concentrations of both siderophores was significantly higher in the presence of hemoglobin than in that of free iron.
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