Simple qualitative tests for rifampicin in urine.

Venkataraman, P.; Narayana, A.S.L; Prabhakar, R.

Indian Journal of Tuberculosis; 1988; 35; 114-116.

Simple qualitative tests for rifampicin in urine, involving extraction with chloroform as well as with benzene were investigated on 50 patients. A positive test result was obtained in 98-100% of the specimens between 3 and 11 hours after drug administration by both methods. All specimens collected prior to administration of rifampicin as also specimens collected after ingestion of other anti-tuberculosis drugs were negative by both methods. However, the chloroform extraction method yielded positive reactions in 26% of 27 specimens collected after the administration of clofazimine.


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