Mycobacteriocin typing of Mycobacterium tuberculosis isolated from patients in South India.

Selvakumar, N.; Vanaja Kumar; Paramasivan, C.N.; Prabhakar, R.

Indian Journal of Medical Research; 1987; 86; 162-164.

A total of 148 strains of M. tuberculosis (South India, 118; Hong Kong, 24; Britain, 6) were screened for mycobacteriocin production by cross-streak method using 9 rapid growers (group IV mycobacteria) as indicator strains adapting the scheme suggested by Takeya and Tokiwa. Eighty six per cent (127 of 148) of the cultures were found typable into two types - type 11 (84%) and type 9 (2%). The remaining 14 per cent (21) cultures were untypable and exhibited different inhibition patterns not reported earlier. Since 98 per cent (125 of 127) of the typable cultures belonged to type 11, the limitation of the present indicator system for typing M. tuberculosis from South India is discussed.


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