Sensitisation pattern of healthy volunteers and tuberculosis patients to various mycobacterial antigens by ELISA.

Sujatha Narayanan; Paramasivan, C.N.; Abdul Ravoof; Narayanan, P.R.; Prabhakar, R.

Indian Journal of Tuberculosis; 1987; 34; 132-135.

Summary: The sensitisation pattern of 39 tuberculosis patients and 21 healthy volunteers to 9 different mycobacterial antigen sonicates was estimated using ELISA. The antibody levels of patients and volunteers were high against M. tuberculosis -7219, M. kansasii and M. scrofulaceum and low against M. chelonei and M. fortuitum . The tuberculosis patients showed a mean antibody level which was significantly different from that of volunteers to M. tuberculosis -7219, M. kansasii , M. scrofulaceum , M. tuberculosis S.I., M bovis and PPD-S. With respect to three antigens, namely, M. chelonei , M. fortuitum and M. avium intracellulare , there was no significant difference between patients and volunteers.


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