Title of the study |
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Name of the Principal Investigator |
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Pharmacokinetic drug-drug interactions between first line anti-TB and anti-diabetic drugs
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Dr. A.K. Hemanth Kumar (hemanthkumarak@nirt.res.in) |
Pharmacokinetics of second-line anti-TB drugs in children and adolescents with MDR TB
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Dr. A.K. Hemanth Kumar (hemanthkumarak@nirt.res.in) |
Bioavailability of fixed dose combination of first line anti-TB drugs in patients with pulmonary tuberculosis
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Dr. A.K. Hemanth Kumar (hemanthkumarak@nirt.res.in) |
Molecular cloning and characterization of full length infectious Transmitted/Founder HIV-1 viruses
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Dr. Luke E. Hanna
(hanna@nirt.res.in) |
Identification of broadly neutralizing antibodies against HIV
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Dr. Luke E. Hanna
(hanna@nirt.res.in) |
Inflammation and aging in HIV-infected individuals on long term antiretroviral therapy
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Dr. Luke E. Hanna
(hanna@nirt.res.in) |
Identification of biomarkers that can predict progression from Latent Tuberculosis Infection to active TB disease
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Dr. Luke E. Hanna
(hanna@nirt.res.in) |
National HIV Cohort Program – Cohorts of HIV Resistance and Progression in Indian Children and Adults (CoHRPICA)
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Dr. Luke E. Hanna
(hanna@nirt.res.in) |
Impact of malnutrition on immune responses to tuberculosis in Indian children
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Dr. Aishwarya Venkataraman
(aishwarya.v@nirt.res.in) |
Development and validation of a diagnostic kit for early detection of Human Papilloma Virus (HPV) infection in cervical cancer
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Dr. N. Sudhakar
(sudhakar@nirt.res.in) |
Latent class analysis of health related quality of life of TB patients during & post treatment in a Longitudinal Design
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Dr. M. Vasantha
(vasantha_m@nirt.res.in) |
Development of a Database of Clinical Study X-rays at NIRT, Chennai
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Dr. C. Ponnuraja
cponnuraja@nirt.res.in) |
HTA for implementation of cell counters for referral of suspected dengue cases at PHC settings
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Dr. M. Muniyandi
(muniyandi.m@nirt.res.in) |
The Economic evaluation of standardised treatment regimens of anti-TB drugs for patients with MDR-TB (STREAM stage-II trial)
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Dr. M. Muniyandi
(muniyandi.m@nirt.res.in) |
Social network analysis as a tool to improve active case finding at community level in Chennai
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Dr. N. Karikalan
(karikalan.n@nirt.res.in) |
Measuring the socio-economic risk-benefits & health related quality of life changes associated with TB disease disclosure
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Dr. N. Karikalan
(karikalan.n@nirt.res.in) |
Early bactericidal activity of anti-tuberculosis drugs
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
Protecting and improving public health globally: Building laboratory, surveillance and workforce capacity to detect, respond to, and prevent drug resistant tuberculosis in India
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
Identification of the latent tuberculosis specific marker by the immunoproteomic analysis of the cell wall and membrane proteins of M. tuberculosis.
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
Accurate, Rapid, Robust and Economical diagnostic technologies for Tuberculosis: ARREST-TB
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
Crohn's disease in India: A multicenter study from a country where intestinal tuberculosis as well as Johne’s disease is endemic
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Dr.P.Kannan
(kannanp@nirt.res.in) |
Studies on epigenome wide alterations in alveolar macrophages during M. tuberculosis infections in guinea pig pulmonary tuberculosis model
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Dr.P.Kannan
(kannanp@nirt.res.in) |
Whole Genome Sequencing and Transcriptome analysis of M. tuberculosis clinical isolates from Bovine and Human Origin
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Dr.P.Kannan
(kannanp@nirt.res.in) |
Identification of Mycobacterium tuberculosis complex (MTBC) organisms in the lymph node samples of slaughtered cattle in Chennai
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Dr.P.Kannan
(kannanp@nirt.res.in) |
Dereplication guided bio-prospecting of cyclic lipopeptides from marine Bacillus sp. for inhibition of M. tuberculosis
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|
DR. P.Kannan
(kannanp@nirt.res.in)
Mentor for the project ;
Dr Sagarika Devi- PI for the project |
Systems biology and immunology of the effect of tuberculosis chemoprophylaxis in HIV infection
|
|
Dr. Syed Hissar
(syed.hissar@nirt.res.in)
and
Dr. Pavan Kumar
(pavankumarn@nirt.res.in) |
An open label, three arm, pragmatic, randomized controlled pilot study to determine the protective effect of Kabha sura kudineer (KSK)/ Nilavembu kudineer (NVK) in preventing COVID19 symptoms compared to standard Vitamin C-Zinc supplementation and to examine immune responses among healthcare workers.
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Dr. Pavan Kumar
(pavankumarn@nirt.res.in)
and
Dr. Subash Babu
(sbabu@nirt.res.in) |
Identification of tuberculosis specific biomarkers in children by the Proteomic analysis of urine.
|
|
Dr.D.Anbarasu
(harianbu@nirt.res.in)
and
Dr. Syed Hissar
(syed.hissar@nirt.res.in) |
Molecular Analysis of monocyte
subsets in humans infected with
Mycobacterium tuberculosis
|
|
Dr.Ramalingam B
(ramalingam.b@nirt.res.in) |
Attenuated mycobacteria based vaccine against tuberculosis with a novel strategy for T cell priming
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
CRISPR mediated platform for diagnosis and rapid detection of drug resistance pattern in M. tuberculosis.
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Dr.K.R. Uma Devi
(umadevi.r@nirt.res.in) |
Functional characterization of oxidoreductases of M. tuberculosis
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Dr.P.Kannan
(kannanp@nirt.res.in) |
Study on Mutations Associated with Pyrazinamide Resistance in M. tuberculosis
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Dr.P.Kannan
(kannanp@nirt.res.in) |
A cross sectional study of the systems immunology and viral diversity of SARS-CoV2 infection, COVID-19 disease and Multisystem Inflammatory Syndrome in children
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|
Dr. Pavan Kumar
(pavankumarn@nirt.res.in)
and
Dr. Subash Babu
(sbabu@nirt.res.in) |
Characterization and Durability of COVID-19 vaccine induced immune responses in healthcare/frontline workers
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|
Dr. Pavan Kumar
(pavankumarn@nirt.res.in)
and
Dr. Banu Rekha
(banurekha@nirt.res.in) |
Humoral and cellular immune response among recovered COVID-19 patients: A cross-sectional study, Tiruvallur district, Chennai Corporation, Tamil Nadu, India, 2020
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|
Dr. Pavan Kumar (Co PI)
(pavankumarn@nirt.res.in) |
Role of neutralizing antibodies and inflammatory biomarkers in children with Paediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS)
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Dr. Pavan Kumar (Co PI)
(pavankumarn@nirt.res.in) |
Regional Prospective Observational Research in Tuberculosis (RePORT) - Phase 2
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Dr. Pavan Kumar (Co PI)
(pavankumarn@nirt.res.in) |
CYP2R1 gene polymorphisms in pulmonary tuberculosis
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Dr. Ramalingam B
(ramalingam.b@nirt.res.in) &
Dr. Harishanker |
Immunomodulation of Autophagy by Vitamin D3 in macrophages Infected with Mycobacterium tuberculosis
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|
Dr. Ramalingam B
(ramalingam.b@nirt.res.in) |
Molecular and immune profiling in adults affected with COVID-19 disease
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|
Dr. N.Sudhakar |
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