Pharmacokinetic drug-drug interactions between first line anti-TB and anti-diabetic drugs

Pharmacokinetics of second-line anti-TB drugs in children and adolescents with MDR TB

Bioavailability of fixed dose combination of first line anti-TB drugs in patients with pulmonary tuberculosis

Molecular cloning and characterization of full length infectious Transmitted/Founder HIV-1 viruses

Dr. Luke E. Hanna
(hanna@nirt.res.in)

Identification of broadly neutralizing antibodies against HIV

Inflammation and aging in HIV-infected individuals on long term antiretroviral therapy

Identification of biomarkers that can predict progression from Latent Tuberculosis Infection to active TB disease

National HIV Cohort Program – Cohorts of HIV Resistance and Progression in Indian Children and Adults (CoHRPICA)

Impact of malnutrition on immune responses to tuberculosis in Indian children

Dr. Aishwarya Venkataraman
(aishwarya.v@nirt.res.in)

Development and validation of a diagnostic kit for early detection of Human Papilloma Virus (HPV) infection in cervical cancer

Dr. N. Sudhakar
(sudhakar@nirt.res.in)

Latent  class analysis of health related quality of life of TB patients during & post treatment in a Longitudinal Design

Dr. M. Vasantha
(vasantha_m@nirt.res.in)

Development of a Database of Clinical Study X-rays at NIRT, Chennai 

Dr. C. Ponnuraja
cponnuraja@nirt.res.in)

HTA for implementation of cell counters for referral of suspected dengue cases at PHC settings

Dr. M. Muniyandi
(muniyandi.m@nirt.res.in)

The Economic evaluation of standardised treatment regimens of anti-TB drugs for patients with MDR-TB (STREAM stage-II trial)

Social network analysis as a tool to improve active case finding at community level in Chennai

Dr. N. Karikalan
(karikalan.n@nirt.res.in)

Measuring the socio-economic risk-benefits & health related quality of life changes associated with TB disease disclosure

Early bactericidal activity of anti-tuberculosis drugs

Protecting and improving public health globally: Building laboratory, surveillance and workforce capacity to detect, respond to, and prevent drug resistant tuberculosis in India

Identification of the latent tuberculosis specific marker by the immunoproteomic analysis of the cell wall and membrane proteins of M. tuberculosis.

Accurate, Rapid, Robust and Economical diagnostic technologies for Tuberculosis: ARREST-TB

Crohn's disease in India: A multicenter study from a country where intestinal tuberculosis as well as Johne’s disease is endemic

Studies on epigenome wide alterations in alveolar macrophages during M. tuberculosis infections in guinea pig pulmonary tuberculosis model

Whole Genome Sequencing and Transcriptome analysis of M. tuberculosis clinical isolates from Bovine and Human Origin

Identification of Mycobacterium tuberculosis complex (MTBC) organisms in the lymph node samples of slaughtered cattle in Chennai

Dereplication guided bio-prospecting of cyclic lipopeptides from marine Bacillus sp. for inhibition of M. tuberculosis

Systems biology and immunology of the effect of tuberculosis chemoprophylaxis in HIV infection

An open label, three arm, pragmatic, randomized controlled pilot study to determine the protective effect of Kabha sura kudineer (KSK)/ Nilavembu kudineer (NVK) in preventing COVID19 symptoms compared to standard Vitamin C-Zinc supplementation and to examine immune responses among healthcare workers.

Identification of tuberculosis specific biomarkers in children by the Proteomic analysis of urine.

Molecular Analysis of monocyte subsets in humans infected with Mycobacterium tuberculosis

Attenuated mycobacteria based vaccine against tuberculosis with a novel strategy for T cell priming

CRISPR mediated platform for diagnosis and rapid detection of drug resistance pattern in M. tuberculosis.

Functional characterization of oxidoreductases of M. tuberculosis

Study on Mutations Associated with Pyrazinamide Resistance in M. tuberculosis

  A cross sectional study of the systems immunology and viral diversity of SARS-CoV2 infection, COVID-19 disease and Multisystem Inflammatory Syndrome in children

Dr. Pavan Kumar
(pavankumarn@nirt.res.in)
and
Dr. Subash Babu
(sbabu@nirt.res.in)

Characterization and Durability of COVID-19 vaccine induced immune responses in healthcare/frontline workers

Humoral and cellular immune response among recovered COVID-19 patients: A cross-sectional study, Tiruvallur district, Chennai Corporation, Tamil Nadu, India, 2020

Role of neutralizing antibodies and inflammatory biomarkers in children with Paediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS)

Regional Prospective Observational Research in Tuberculosis (RePORT) - Phase 2

CYP2R1 gene polymorphisms in pulmonary tuberculosis   

Immunomodulation of Autophagy by Vitamin D3 in macrophages Infected with Mycobacterium tuberculosis